Hoxa genes: regulation in adult uterus by estrogen and progesterone and repression in mullerian duct by the synthetic estrogen diethyl-
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چکیده
Cox DR, Oakes D. Analysis of survival data. London, UK: Chapman Hall, 1984. 20 Newbold RR. Lessons learned from perinatal exposure to diethylstilbestrol. Toxicol Appl Pharmacol 2004;199:42–150. 21 Walker BE, Uterine tumors in old female mice exposed prenatally to diethylstilbestrol. J Natl Cancer Inst 1983;70:177–81. 22 Newbold RR, McLachlan JA. Vaginal adenosis and adenocarcinoma in mice exposed prenatally or neonatally to diethylstilbestrol. Cancer Res 1982;42:2003–11. 23 McLachlan JA, Newbold RR, Bullock BC. Long-term effects on the female mouse genital tract associated with prenatal exposure to diethylstilbestrol. Cancer Res 1980;40:3988–99. 24 McLachlan JA, Newbold RR, Shah HC, Hogan M, Doxon RL. Reduced fertility in female mice exposed transplacentally to diethylstilbestrol (DES). Fertil Steril 1982;38:364–71. 25 McLachlan JA, Burow M, Chiang T-C, Li SF. Gene imprinting in developmental toxicology: a possible interface between physiology and pathology. Toxicol Lett 2001;120:161–64. 26 Li S, Hursting SD, Dzvis BJ, McLachlan JA, Barrett JC. Environmental exposure, DNA methylation, and gene regulation. Lessons from diethylstilbesterol-induced cancers. Ann N Y Acad Sci 2003;983:161–69. 27 Li JJ, Hansman R, Newbold R, Davis B, McLachlan JA, Barrett JC. Developmental exposure to diethylstilbestrol elicits demethylation of estrogen-responsive lactoferrin gene in mouse uterus. Cancer Res 1997;57:4356–59. 28 Couse JF, Dixon D, Yates M et al. Estrogen receptor-a knockout mice exhibit resistance to the developmental effects of neonatal diethylstilbestrol exposure on the female reproductive tract. Dev Biol 2001;238:1–15. 29 Mericskay M, Carta L, Sassoon D. Diethylstilbestrol exposure in utero: A paradigm for mechanisms leading to adult disease. Birth Defects Res A Clin Mol Teratol 2005;73:133–35. 30 Kamiya K, Sato T, Nishimura N, Goto Y, Kano K, Iguchi T et al. Expression of estrogen receptor and proto-oncogene messenger ribonucleic aids in reproductive tracts of neonatally diethylstilbestrolexposed female mice with or without post-pubertal estrogen administration. Exp Clin Endocrinol Diabetes 1996;104:111–12. 31 Yamashita S, Takayanagi A, Shimizu N. Effects of neonatal diethylstilbestrol exposure on c-fos and c-jun protooncogene expression in the mouse uterus. Histol Histopathol 2001;16:131–40. 32 Falck L, Forsberg J-G. Immunohistochemical studies on the expression and estrogen dependency of EGF and its receptor and C-fos proto-oncogene in the uterus and vagina of normal and neonatally estrogen-treated mice. Anat Rec 1996;245:459–71. 33 Ma L, Benson GV, Lim H, Dey SK, Maas RL. Abdominal B (AbdB) Hoxa genes: regulation in adult uterus by estrogen and progesterone and repression in mullerian duct by the synthetic estrogen diethylstilbestrol (DES). Dev Biol 1998;197:141–54. 34 Block K, Kardana A, Igarashi P, Taylor HS. In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing mullerian system. FASEB J 2000;4:1101–08. 35 Sato T, Ohta Y, Okamura H, Hayashi S, Iguchi T. Estrogen receptor (ER) and its messenger ribonucleic acid expression in the genital tract of female mice exposed neonatally to tamoxifen and diethylstilbestrol. Anat Rec 1996;44:74–385. 36 Okada A, Sato T, Ohta Y, Buchanan DL, Iguchi T. Effect of diethylstilbestrol on cell proliferation and expression of epidermal growth factor in the developing female rat reproductive tract. J Endocrinol 2001;170:539–54. 37 Wilcox AJ, Umbach DM, Hornsby PP, Herbst AL. Age at menarche among diethylstilbestrol granddaughters. Am J Obstet Gynecol 1995;73:835–36. 38 Perez K, Titus-Ernstoff L, Hatch EE et al. Reproductive outcomes in men with prenatal exposure to DES. Fertil Steril 2005;84:1649–56. 39 Kaufman RH, Adam E. Findings in female offspring of women exposed in-utero to diethylstilbestrol. Obstet Gynecol 2002;99:197–200.
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